Agmatine Sulphate
BENEFITS:
MUSCLE PUMPS
Agmatine has built itself a reputation in the bodybuilding community for its ability to create huge muscle pumps through its Nitric oxide regulation. Nitric oxide is a compound naturally produced in your body that plays a role in cell signaling and communication throughout your entire system. Anecdotally, this enhanced connection also may promote one’s sense recognition and support feelings of well being. Agmatine sulfate is even used as an ingredient in various pre-workouts and “pump” supplements. In fact, it’s quite common to pair a pre-workout with agmatine sulfate and some athletes swear by the agmatine sulfate bodybuilding benefits.
NOOTROPIC EFFECT:
Agmatine sulfate also appears to interact with NMDA glutamate receptors. Once these receptors are activated, they allow positively charged ions to flow through cell membranes. NMDA receptors are also one of the key glutamate receptors involved in regulating memory functions and synaptic plasticity. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.
As a novel neurotransmitter, agmatine is created and destroyed in neurons at the site that it is also stored. This mechanism allows agmatine to regulate neurotransmission which helps prevent excitotoxity. Neurotransmitter regulation improves significantly in NMDA receptors, which play crucial roles in memory and learning following agmatine supplementation.